PhD (all gender) - Department of Nephrology and the Else Kroener-Fresenius Center for Nephrological Research
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Frankfurt am Main
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PhD (all gender) - Department of Nephrology and the Else Kroener-Fresenius Center for Nephrological Research
Frankfurt am Main
Aktualität: 28.11.2025
Anzeigeninhalt:
28.11.2025, Universitätsklinikum Frankfurt
Frankfurt am Main
PhD (all gender) - Department of Nephrology and the Else Kroener-Fresenius Center for Nephrological Research
Aufgaben:
Processing, quality control and analysis of scRNA-seq, scATAC-seq and spatial transcriptomics datasets
Implementation and adaptation of machine-learning and AI methods for cell type identification, trajectory inference and regulatory network analysis
Integration of multi-omics data (e.g. genomics, transcriptomics, epigenomics) with large-scale cohorts such as UK Biobank
Collaboration with experimental and clinical researchers to define hypotheses and interpret results in a biological and clinical context
Presentation of results within the working group, at seminars and conferences
Writing of a PhD thesis and contribution to scientific publications
Very good command of English (spoken and written); German is an advantage but not required
High motivation, ability to work independently as well as in an interdisciplinary team, good organizational and communication skills
Due to legal regulations, valid proof of measles immunity / measles vaccination is required.
Qualifikationen:
- Processing, quality control and analysis of scRNA-seq, scATAC-seq and spatial transcriptomics datasets
- Implementation and adaptation of machine-learning and AI methods for cell type identification, trajectory inference and regulatory network analysis
- Integration of multi-omics data (e.g. genomics, transcriptomics, epigenomics) with large-scale cohorts such as UK Biobank
- Collaboration with experimental and clinical researchers to define hypotheses and interpret results in a biological and clinical context
- Presentation of results within the working group, at seminars and conferences
- Writing of a PhD thesis and contribution to scientific publications
- Very good command of English (spoken and written); German is an advantage but not required
- High motivation, ability to work independently as well as in an interdisciplinary team, good organizational and communication skills
- Due to legal regulations, valid proof of measles immunity / measles vaccination is required.
Wir bieten:
The PhD project is embedded in a translational research program aiming to understand how the hematopoietic system connects cardiovascular and kidney diseases. Using single-cell and spatial omics as well as large population-based datasets, the project will identify molecular and cellular mechanisms driving cardiovascular complications in kidney disease.
Processing, quality control and analysis of scRNA-seq, scATAC-seq and spatial transcriptomics datasets
Implementation and adaptation of machine-learning and AI methods for cell type identification, trajectory inference and regulatory network analysis
Integration of multi-omics data (e.g. genomics, transcriptomics, epigenomics) with large-scale cohorts such as UK Biobank
Collaboration with experimental and clinical researchers to define hypotheses and interpret results in a biological and clinical context
Presentation of results within the working group, at seminars and conferences
Writing of a PhD thesis and contribution to scientific publications
Berufsfeld
Öffentlicher Dienst, Verwaltung
Gesundheits-/Sozialwesen
Medizin, Ärztlicher Dienst
Forschung, Lehre
Forschung & Entwicklung
Biologische, Klinische F&E
Bundesland
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